Better Homes And Gardens 2008 06, page 102 read online

H earteardv

—

--------rw .

(ivermectin.pyrantel)

CHEWABLES

CAUTION:

Fodcf.il U SA aw rcst'cts this drug

use by or on the crdci

of a licensed veterinarian

INDICATIONS: :or use in dogs to prevent canine haanwctm disease bv elimirating

the tissue stage pf beartworm larvae

(D irofiiana

imrofs/for a month 130 days) after

infection dno Tu' tilt treatment ami central cf asaanls i7u«.rara

ukus. fotaswis

.tco'wiajand hoo<v;orrr.s

(A c c y fo s x m m

i f w . U r x m ’ io s to -v x c p te b .

Ancyiostcm d I v m '.’ensei

DOSAGE

IEARTGARD '. Pus ir.crmc. t' i VvauW! OwwcWes should be adtonstoroc

crslly at roanthlv ntevdis a: the

rectntrrenfel

m inrun ckse ter.ei of

rrcg cf iw=n:Ktr

per kiitgan (2 /2 meg

b- and 5 mg cf p/rarcel las pamoate aft) per kg {227 rrg'b) of beev

rtenht.'71« learnmenJed dosing schetMe

x r

prevention of

ire heaitwoni

ctææe

and

for the

tra3tirent

and oontrof of ascar ds aid texfcxvonits is as falows:

Dog

Chewables

W eight Per M onth

Ivem iectm

Content

Pyrantel

Content

Color Coding 0«

Foil-Backing

and Carton

Цр to 2S

6£ mg

57 mg

Blue

2Б 50

-Sncg

•M rrg

Greet

51-100

272 neg

227 rro

Brawl

HEARTGARD Plus is recon mended for dcqs 6 weeks of ago aid older. For dogs errer

100 lb use the appropriate combination of these chewables

ADMINISTRATION:

Retrcvc cnlyonc clxwable at a trie from the fui cjdwti blister

card Return the card with the r6mairino chaivabre to its box ta crotec. the prcdxt

frem Inht Because most decs ;md HEARTGARD Plus peiatabe the product can be

offered to the dog b> hand. Alternatively, it irav te adeted intact to a snail airourt of

dog fcod.The clxvrable slxiuid be administered in a manner that encourages die deg

to chirr.', ratter than to swallow v.ithout ciawing Cnawablas may be bro<an into

pieces and fed to dogs bat ncmaly swalow treats whole.

Care s-iould be taken that the dog ccreumes the compete cose, arid treated animals

should be cbje-vsd for a few minutes after admnistraticn to ensure that part cr the

dose is rot test or rejected If t is suspected that

of the dose has been lost

redosing is recoimterded.

HEARTGARD Plus should te gver at monthly intervals during the period of the yea'

when niospuitots (vectors^ potentially carrying

111

(

00111

« beartworm larvae, are

act<vo. Tho initio1

doto muct bo givoo

within 0

morrh (30 daye) oftor tho doo'e first

exposjre to mosquitoes. The final dose must be given within a month 130 rays)

alter die deg’s last ensure to masquitoes.

When replacing ancther heartwo-m preventive product in a beartworm disease

prevention program, the fust dose of HtARTGAftD Plus must be given within a

nxnth 130 days) of tte iast dose of the former rustication

if the interval between doses exceeds a month i30davsl, the efficacy of ivermectin

can be reduced. Therefore, for optimal performance. the chewable must te given

once a month on or about the same day of the month If treatment s delayed,

wfether л- a few days or тагу, immediate treatment with HEARTGARD Plus and

resumption of the recommended dosing regmei w II minimize the opportunity for

thB devebpment of adult heattwarms.

Monttily t-earnerl with HEARTGARD Bus also provides effective treatment ard ocntrpl

of ascands

j J cams. I

.feawra.iandtemvwoims

(А

сатшд

sra-хщЛаСз,

A .

b m tim s a ).

Clients should :o advised af measure to be taken to praveit reinfaction

w(h intestinal parasites

EFFICACY:

HEARTGARD Rus Chewables. given oia lv using me recommendec

dose and regmen.

y e

e'fectrve against the tissue larval stage oi

D .ir m itis

fot a

month 130 davsl alter mtection and, as a result, prevent the Sevewpmem or the

adult stage HEARTGARD Plus Chewables are also effective

-»1 canine ascadds

1 cam s

7 tetywra) and hookworms |A eamnum

U s te n o c e ffa la . A txa/Aiense).

ACCEPTABILITY

In acceptability and fiekl trial* HEARTGARD Plus Chewables were

shown to be an acceptable oral drear»? lam that was renamed at hr» offering by the

majority of dogs,

PRECAUTIONS:

AH cogs shoulc be tested for existing hearwem mfeeben before

starting treamert with HEARTGARD Plus which is rot effect;-.« agairts* adult

лгопйв. Infected dogs trust be treated to remove aclrlt beartv/unis ard microfilariae

before initiabrg a program with HEARTGARD Plus.

While sore microfilariae irav be hi ed by the ivennectir in HEARTGARD Plus at the

reccnvmrded dose level, HFARTGARI) P js « not effective for microfilariae clearance.

Л mild liypeseistivdy-type react kn. presumably due to dead cr dying microfilariae

and particularly involving a transient diarrhea. has been observed in clinical trels with

ivermectin alone alter treatment ol some dogs dial lave circulating microfilariae

Keep this and all drugs out of the reach of children.

In сада ol ingestion by -omare. clients should he advised to contact a physician

immediately. Rivsioans may contact a Fbison Control Center for advice concerning

cases of ngesticn by humans

Store at controlled гост temusralure of 68£f - 77°f (20°C - 25°Cl. Excursions

between 59 F ■

867 |15°C -

30nCl are permitted. ^otect product from light

ADVERSE REACTIONS: h clinical feln trials with HEARTGARD Plus, vwnitiig or

drerrtea within 24 hoots of dosing was randy observed 11.1е!» of administered

drees) Tie loi lowing adverse react ens have been reported following the use of

HEARTGARD: Depressron/bthaigy. vomiting, anorexia, diarrhea, myc-iasis. ataxia,

staggering, convulsions and hypersalivation

SAFETY: HEARTGARD Plus has bean shown to be boequr,ateit to HEARTGARC vwtfl

respect tc tte bicovu. Lability of ivermectin The cose teamens of HEARTGARD Pus

and HEARTGARD are the same win regard to ivermectin 16 megfe). Studes wita

ivermectin irmcate that ce-tam dags or the Co ib b'eed are more sersitr.e to the

effects os ivermectin administered a: elevated dose levels foiore than 16 times the

target use level) than ckgs of other breeds. At elevated doses, sersitne dogs slowed

advene reactions which induced mydriasis, degression ataxia, tremers. drooling

paresis, recumbency e»c tebilily. stupor, ccma and death HEARTGARD demenstrated

nosigis of toxety at 10 tines die recommended dose 60mcg>'kgl insensitive

Colliw Pcoult3 of thcec trials ond oiocqurvolorcv studies, эиреоп the ootetv of

HEAR'GAflDfiioli.cls in degs inchidwg Collies, when used asraammentteil

HEARTGARD Rus has shown a wide margin of safety at the recommended dose

level in dags, including pregnant cr breeding btchre. stud dogs and puppies aged 6

cr more weeks In cimcal trials, many commonly used Ilea celars. dips, shampoos,

arr.hehiirtics. antibiotics, vaccines and sterod pceparanons have been administered

with HEARTGARD Rus in a heartworm d'Sosse prevention program.

In ore trial, where seme pups bed parvovirus, there was a marginal reduction n efficacy

against intestinal nematodes, possibly die to a change in intestinal transit time

HOW SUPPLIED:

lEARTQARC Rus is avaiiabfe in three dotage strengths (see

DC'SAGE section) for degs of different weighs Each strength ccmes in oorvement

canons of 6 and 12 chewables.

For customer sernce. please contact Menal at 1-888-6374251

Of dogs showing а те^агепда in th-ee studies conducted ay rdepenJert rr.estqatcrs,

dogs prefcried HEARTGARD Rus u«i IWIEF£EP[ORft(-nilKiir>u:nc«iiiiH|’

FLAVOR TA8SS by a matgn of 37.1. cista on file ut Medal.

Market D,roincs; Mcrthfy share reprt. 'itit dspensad treatments; 12ДИ/07.

data on life at Medial

MGRIAL

tSHEARIGARD and foe Dog & Herd logo are registered troierrorks of Meriol

OÏWTERCETTW is о registered Irademak of fe Notrorfis (erperntijn

IN THE GARDEN

p lain la w n w ith a fe w o v e rg ro w n s h ru b s

w a s an in v ita tio n fo r L eila G re e n to s ta rt

dig g in g . A fte r sh e m o v e d in to h e r

W arw ick , R h o d e Isla n d , c o tta g e in 1991,

^ / “th e b u s h e s w e n t first,” L eila says, “th e n

I ju s t s ta r te d p u llin g u p g rass.” F u e le d b y h e r love o f

g a rd e n in g a n d a p re fe re n c e fo r flo w ers o v e r tu rf, L eila

so o n tu rn e d m o st o f h e r 5 0 xlO O -foot lo t in to a b lo o m in g

h e a d -tu rn e r.

T h e g a rd e n is p la n te d a lm o st e n tire ly w ith p e re n n ia ls

a n d a few a n n u a ls to fill in th e g ap s. “I love th e b illo w y

E n g lish c o tta g e sty le a n d lo ts o f flo w ers,” says L eila.

“N o w th e r e ’s o n ly a little p a tc h o f g ra ss left,” sh e says.

“B u t p ro b a b ly n o t fo r long.”

100

JUNE 2008 BETTER HOMES AND GARDENS